Mount Sinai Rolls Out AI-Powered Medical Search and Clinical Decision-Support Platform

Health Data SystemsTelehealth & Remote CareHealth Monitoring

Mount Sinai Health System is taking a significant step forward in healthcare innovation by rolling out OpenEvidence, an AI-powered medical search and clinical decision-support platform.

TL;DR
• Mount Sinai Health System is rolling out OpenEvidence, an AI-powered medical search and clinical decision-support platform.
• The platform is designed to provide clinicians with a unified, trusted platform for evidence-based decision-making.
• OpenEvidence is the first enterprise-scale deployment that explicitly extends access across the entire clinical care team.

Summary
Mount Sinai Health System, a leading academic medical network, is integrating OpenEvidence, an AI‑driven medical search and clinical decision‑support platform, directly into its Epic electronic health record. This rollout marks the first time the system is made available to the entire clinical care team, including physicians, registered nurses, and pharmacists.

OpenEvidence operates as a highly governed search engine that delivers answers strictly sourced from peer‑reviewed literature and clinical guidelines, thereby minimizing hallucinations. Clinicians can pose complex, natural‑language questions at the bedside, and the AI synthesizes evidence‑based responses with direct citations. By embedding the tool within Epic, the platform addresses the “last mile” challenge, ensuring pharmacists and nurses can access drug interaction guidelines without leaving their workflow.

The expansion reflects a strategic shift toward democratizing evidence‑based decision‑making across multidisciplinary teams. By providing nurses and pharmacists with the same trusted platform as physicians, the deployment supports a culture of shared knowledge and collaborative care. The integration also signals a commitment to transparency, as every answer is traceable to its source, fostering confidence in AI‑assisted clinical judgments.

This initiative underscores the importance of aligning technology with existing clinical processes and workforce needs. By embedding AI directly into routine workflows, the system promotes seamless adoption and continuous learning. The approach illustrates how thoughtful design can enhance patient safety, support workforce development, and maintain rigorous standards for evidence and ethics in healthcare technology.

As healthcare continues to evolve, it's essential to prioritize innovation and evidence-based decision-making. By implementing OpenEvidence, Mount Sinai Health System is setting a new standard for clinical AI adoption and demonstrating its commitment to improving patient outcomes.